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Immunotherapy

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Immunotherapy

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Immunotherapy, also known as biologic therapy or biotherapy, is a cutting-edge cancer treatment that works by enhancing the body’s natural defense mechanism….

What is Immunotherapy?

Immunotherapy, also known as biologic therapy or biotherapy, is a cutting-edge cancer treatment that works by enhancing the body’s natural defense mechanism, the immune system, to fight cancer cells. Unlike traditional treatments like chemotherapy and radiation, which directly target cancer cells, immunotherapy stimulates the body’s immune system to recognize and attack cancerous cells more effectively.

How Does Immunotherapy Work?

There are various types of Immunotherapy, each designed to target different aspects of the immune system and cancer cells. Some common approaches include:

  1. Checkpoint Inhibitors: Cancer cells can sometimes evade the immune system by expressing certain proteins known as checkpoints. Checkpoint inhibitors block these proteins, allowing the immune system to recognize and attack cancer cells more effectively.
  2. CAR T-cell Therapy: This personalized treatment involves collecting a patient’s T-cells (a type of immune cell) and genetically engineering them to express chimeric antigen receptors (CARs). These modified T-cells are then infused back into the patient’s body, enabling them to target and destroy cancer cells more efficiently.
  3. Cytokines: These are naturally occurring proteins that regulate the immune system. Immunotherapy can involve the administration of specific cytokines to strengthen the body’s ability to fight cancer.
  4. Cancer Vaccines: Unlike preventive vaccines, cancer vaccines stimulate the immune system to target existing cancer cells. These vaccines can be based on cancer cell fragments, specific proteins, or genetically modified cancer cells.
  5. Monoclonal Antibodies: These are laboratory-produced antibodies that can recognize and target specific proteins on cancer cells, marking them for destruction by the immune system.

Conditions Treated with Immunotherapy:

Immunotherapy has shown remarkable success in treating various types of cancer, including but not limited to:

  • Melanoma (skin cancer)
  • Non-small cell lung cancer
  • Renal cell carcinoma (kidney cancer)
  • Bladder cancer
  • Head and neck cancer
  • Hodgkin’s lymphoma
  • Leukemia
  • Liver cancer
  • and more.

Benefits of Immunotherapy:

Immunotherapy offers several advantages over traditional cancer treatments, such as:

  1. Targeted Therapy: Immunotherapy focuses on cancer cells while sparing healthy cells, leading to fewer side effects compared to chemotherapy and radiation.
  2. Long-term Response: Some patients experience long-lasting responses to immunotherapy, with cancer staying in remission for extended periods.
  3. Combination Therapy: Immunotherapy can be used in combination with other treatments to enhance their effectiveness.
  4. Improved Quality of Life: With fewer side effects, patients often experience an improved quality of life during treatment.

Limitations and Considerations:

While Immunotherapy has shown significant promise, it may not be suitable for every cancer patient. Factors such as cancer type, stage, and overall health are essential considerations when determining the most appropriate treatment plan. Additionally, some patients may experience immune-related side effects, which your oncologist will closely monitor and manage.

Do’s:

  1. Stay Informed
  2. Follow Treatment Schedule
  3. Maintain a Healthy Lifestyle
  4. Keep Hydrated
  5. Report Symptoms Promptly
  6. Stay Protected from Infections
  7. Monitor Your Skin
  8. Maintain Open Communication

Don’ts:

  1. Miss or Skip Doses
  2. Use Over-the-Counter Medications Without Consultation
  3. Ignore Side Effects
  4. Consume Alcohol or Tobacco
  5. Discontinue Treatment Without Consulting Your Oncologist